Cabazitaxel

None of the guidelines names a specific antidote or compress for this drug. See the general recommendations.

References

Risk class: Irritant with vesicant propertiesONS/ASCO 2025 (Table 1, p. 385)

Not classified in: ESMO-EONS 2012, JSCN/JSMO/JASPO 2024

ONS/ASCO 2025Irritant with vesicant properties
Antimicrotubule agents, taxanes
Table 1, p. 385

Not classified in: ESMO-EONS 2012, JSCN/JSMO/JASPO 2024

Brand names (ANVISA, Brazil) · DCB (Brazil)

DCB (Brazil)cabazitaxel (nº 9820)

Brand names (ANVISA, Brazil)CAAB, CABAZRED, JEVTANA, PROAZITAX

General recommendations of the guidelines

ONS/ASCO 2025Recommendation 1 · Strong; very low
Use antidotes, when one exists, for vesicants and irritants with vesicant properties, rather than no antidote.
Table 3, p. 388
ONS/ASCO 2025Recommendation 3 · Conditional; very low
Thermal compress (cold or warm depending on the agent) rather than no compress.
Table 3, p. 388
ONS/ASCO 2025Recommendation 4 · Conditional; very low
Compress for more than 24 hours rather than 24 hours or less.
Table 3, p. 388
ONS/ASCO 2025Recommendation 5 · Conditional; very low
Central line extravasation: surgical referral or escalation of care in addition to conservative management.
Table 3, p. 388
JSCN/JSMO/JASPO 2024CQ10a · Recommend (weak)
Cold compression (weak recommendation).
Table 1, CQ10a
JSCN/JSMO/JASPO 2024CQ10b · Not recommend (weak); D
Non-use of warm compresses (weak recommendation).
Table 1, CQ10b